可的松对大鼠肝脏线粒体的影响。
Effects of cortisone on rat liver mitochondria.
作者信息
LOWE C U, MACKINNEY D, SARKARIA D
出版信息
J Biophys Biochem Cytol. 1955 May 25;1(3):237-44. doi: 10.1083/jcb.1.3.237.
Abstract
Experiments were designed to determine the effects of parenteral administration of cortisone on mitochondrial numbers of rat liver cells. Observations were made in three ways: (1) after osmic acid fixation and appropriate stain, (2) by phase microscopy on intact cells, (3) by actual enumeration of mitochondria and nuclei to provide data on mitochondria per cell. The results of the experiments indicate that the mitochondria per cell are significantly reduced under the conditions used. Each experimental approach provided similar data, and each tended to support the results obtained from the others.
摘要
实验旨在确定肠胃外注射可的松对大鼠肝细胞线粒体数量的影响。通过三种方式进行观察：（1）经锇酸固定和适当染色后；（2）利用相差显微镜观察完整细胞；（3）实际计数线粒体和细胞核以提供每个细胞中线粒体的数据。实验结果表明，在所采用的条件下，每个细胞中的线粒体数量显著减少。每种实验方法都提供了相似的数据，且每种方法都倾向于支持其他方法所获得的结果。
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Anat Rec. 1952 Apr;112(4):797-809. doi: 10.1002/ar.1091120406.
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Effect of cortisone administration upon nucleic acid composition of rabbit liver.可的松给药对兔肝脏核酸组成的影响。
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Effect of cortisone administration on intracellular composition of rat liver.可的松给药对大鼠肝脏细胞内成分的影响。
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