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[试验对象血液中碳氧血红蛋白含量及呼出气体中一氧化碳含量与密闭舱空气中一氧化碳浓度的关系]

[Relationship of the content of carboxyhemoglobin in the blood and of carbon monoxide in the expired air of test subjects to the CO concentration in the air of a hermetic chamber].

作者信息

Savina V P, Sokolov N L, Nikitin E I

出版信息

Kosm Biol Aviakosm Med. 1976 Nov-Dec;10(6):62-6.

PMID:13244
Abstract

Four manned experiments (4 test subjects participating in each) were carried out in a chamber of 24 m3. The effect of CO at a concentration of 10 to 45 mg/m3 on the content of carboxyhemoglobin in the blood, nonhemoglobin iron in the plasma, CO in the breathing air, catalase and peroxidase activity was studied. A correlation was found between these parameters and CO concentration in the atmosphere and exposure time. It was demonstrated that a continuous exposure (up to 90 days) to CO at a concentration of 10 mg/m3 under favorable microclimatic conditions produced no significant effect on the above mentioned biochemical paramters.

摘要

在一个24立方米的舱室内进行了四项载人实验(每项实验有4名受试者参与)。研究了浓度为10至45毫克/立方米的一氧化碳对血液中碳氧血红蛋白含量、血浆中非血红蛋白铁含量、呼吸空气中的一氧化碳含量、过氧化氢酶和过氧化物酶活性的影响。发现这些参数与大气中一氧化碳浓度和暴露时间之间存在相关性。结果表明,在有利的微气候条件下,连续暴露于浓度为10毫克/立方米的一氧化碳(长达90天)对上述生化参数没有显著影响。

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