Munford A G
J Am Dent Assoc. 1976 Jul;93(1):121-4. doi: 10.14219/jada.archive.1976.0603.
Two cases of Papillon-Lefevre syndrome have been seen in the same family. The characteristic features of the syndrome are shown to be present in both children and the main characteristics are hyperkeratosis of the palms of the hands and soles of the feet; destruction of the periodontium of the deciduous teeth with subsequent premature loss of the teeth; and destruction of the periodontium of the permanent teeth and the premature loss of these teeth usually before 16 years of age.
在同一家庭中发现了两例帕皮永-勒费弗尔综合征病例。该综合征的特征在两个孩子身上均有体现,主要特征包括手掌和脚底的角化过度;乳牙牙周组织破坏,随后牙齿过早脱落;恒牙牙周组织破坏,这些牙齿通常在16岁之前过早脱落。