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Papillon-Lefèvre syndrome. Report of two patients treated successfully with isotretinoin.

作者信息

Nguyen T Q, Greer K E, Fisher G B, Cooper P H

出版信息

J Am Acad Dermatol. 1986 Jul;15(1):46-9. doi: 10.1016/s0190-9622(86)70140-0.

Abstract

The Papillon-Lefèvre syndrome is an autosomal recessive disorder characterized by diffuse palmoplantar keratoderma and premature loss of both the deciduous and the permanent teeth. We report two female patients with Papillon-Lefèvre syndrome in whom treatment with oral isotretinoin produced remarkable improvement of the keratoderma within 2 weeks.

摘要

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