Narayana L, Nagarajan L
Department of Hematology, University of Texas M.D. Anderson Cancer Center, Houston 77030.
Gene. 1992 Sep 10;118(2):297-8. doi: 10.1016/0378-1119(92)90205-4.
The mouse c-ros protooncogene genomic sequences have been cloned; an analysis of the partial genomic clone revealed a high conservation of the exons encoding the juxta-membrane (JM) and the 5' most protein tyrosine kinase domains. We have identified a segment of 22 amino acids conserved between the human and mouse JM domains; this segment may have a critical role in the function of the c-ros-encoded protein tyrosine kinase receptor.
