Paul S R, Merberg D, Finnerty H, Morris G E, Morris J C, Jones S S, Kriz R, Turner K J, Wood C R
Genetics Institute, Inc., Cambridge, Massachusetts.
Int J Cell Cloning. 1992 Sep;10(5):309-14. doi: 10.1002/stem.5530100509.
Receptor tyrosine kinases mediate a range of growth and differentiation processes in multiple biological systems. In this work, we report the identification of a novel tyrosine kinase-related molecule, nyk-r, and the molecular cloning of its complete cDNA. Its extra-cellular domain bears no apparent homology with other receptor families, but its intracellular kinase-related region has considerable similarity with members of the insulin-receptor family such as c-met and trk B. Also, the nyk-r gene is expressed in a wide range of tissues and cell lines.
