Meldrum B S
Department of Neurology, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, UK.
Curr Opin Neurol Neurosurg. 1992 Aug;5(4):508-13.
Recent advances in the molecular biology of excitatory amino acid receptors are reviewed. Evidence that drugs blocking the excitatory action of glutamate at the N-methyl-D-aspartate (NMDA) and non-NMDA receptors may be of clinical use in epilepsy, Parkinson's disease, cerebral ischaemia and trauma, acquired immune deficiency syndrome (AIDS) encephalopathy and neuropathic pain is summarized.
本文综述了兴奋性氨基酸受体分子生物学的最新进展。概述了如下证据：阻断谷氨酸在N-甲基-D-天冬氨酸（NMDA）受体和非NMDA受体处的兴奋作用的药物，可能在癫痫、帕金森病、脑缺血和创伤、获得性免疫缺陷综合征（AIDS）脑病以及神经性疼痛的治疗中具有临床应用价值。
