Russi E G, Pergolizzi S, Mesiti M, Rizzo M, d'Aquino A, Altavilla G, Adamo V
Institute of Oncology and Research on Cancer (IORC), University of Messina, Italy.
Cancer. 1992 Sep 15;70(6):1483-7. doi: 10.1002/1097-0142(19920915)70:6<1483::aid-cncr2820700606>3.0.co;2-0.
The authors report a patient with iatrogenic dissemination of hepatocellular carcinoma (HCC). A 65-year-old Caucasian man was found to have a moderately well-differentiated HCC diagnosed by laparoscopy and biopsy; the patient had atypical left liver lobe resection. Thirty-three months after definitive surgery a double relapse was found at the site of the previous laparoscopy and at the surgical scar; no other metastases were found. Surgical procedure for removal of these lesions was performed, and the patient received complementary radiation therapy. At 30 months of follow-up, the patient is alive and disease free. The risk of neoplastic seeding through biopsy and improved safety in surgical techniques justify the omission of diagnostic biopsy in patients who have surgical procedures.
作者报告了一例医源性肝细胞癌（HCC）播散的患者。一名65岁的白种男性经腹腔镜检查和活检被诊断为中度分化良好的HCC；该患者接受了非典型左肝叶切除术。根治性手术后33个月，在先前腹腔镜检查部位和手术瘢痕处发现双复发；未发现其他转移灶。对这些病灶进行了手术切除，患者接受了辅助放疗。随访30个月时，患者存活且无疾病。通过活检导致肿瘤种植的风险以及手术技术安全性的提高证明了对于接受手术的患者可省略诊断性活检。
