七例原发性结直肠癌的直接染色体分析

Direct chromosome analysis of seven primary colorectal carcinomas.

作者信息

Xiao S, Wei W, Feng X L, Shi Y H, Liu Q Z, Li P

机构信息

Department of Biology, Harbin Medical College, China.

出版信息

Cancer Genet Cytogenet. 1992 Aug;62(1):32-9. doi: 10.1016/0165-4608(92)90034-6.

DOI:10.1016/0165-4608(92)90034-6

PMID:1325867

Abstract

Chromosome studies were performed on direct preparations of seven cases of primary colorectal carcinomas. Two cases had relatively simple chromosome changes: 48,XY,+8,+21/51, XY,+8,+9,+10,+i(17q),+21, and 47,der(X)t(X;14)(q11;q11)-Y,t(6;18)(p22;q24)+7,+8,der(19)t (19;?)(q13;?). The five others had complicated deletions and translocations; 1p- was noted in five cases, and i(17q) was noted in three cases.

摘要

对7例原发性结直肠癌的直接标本进行了染色体研究。2例有相对简单的染色体改变：48,XY,+8,+21/51,XY,+8,+9,+10,+i(17q),+21，以及47,der(X)t(X;14)(q11;q11)-Y,t(6;18)(p22;q24)+7,+8,der(19)t(19;?)(q13;?)。另外5例有复杂的缺失和易位；5例中发现1p-，3例中发现i(17q)。