Gusev E I, Demina T L, Boĭko A N, Tatarinova M Iu
Zh Nevropatol Psikhiatr Im S S Korsakova. 1992;92(2):14-8.
The clinico-immunologic monitoring of 50 patients suffering from genuine multiple sclerosis by means of the clinical, neurophysiological and immunologic methods and NMR tomography attests to the relationship between changes in the clinical and immunologic characteristics. The changes in the immunologic characteristics were found to anticipate the clinical ones. The authors provide evidence for the possibility and necessity of the clinico-immunologic monitoring of the patients' status for predicting the further course of the disease.
通过临床、神经生理学、免疫学方法以及核磁共振断层扫描技术，对50例真性多发性硬化症患者进行临床免疫学监测，证实了临床特征与免疫特征变化之间的关联。研究发现免疫特征的变化先于临床特征的变化。作者提供了证据，证明对患者病情进行临床免疫学监测对于预测疾病的进一步发展具有可能性和必要性。
