[多发性硬化症中的细胞免疫特征]
[Characteristics of cellular immunity in multiple sclerosis].
作者信息
Demina T L, Boĭko A N, Balashov K E, Pinegin B V
出版信息
Zh Nevropatol Psikhiatr Im S S Korsakova. 1989;89(2):35-41.
PMID:2524943
Abstract
In 30 patients with definite multiple sclerosis a combined clinicoimmunological investigation was performed. The results of estimation of T-lymphocyte subpopulations by means of flow cytometry and monoclonal antibodies; of proliferative responses to PHA, PWM and Con A, to PHA with autoserum; of synthesis and reception of IL-2 containing material is discussed. A hypothesis of a cyclic course of the immunopathologic process is suggested (autoimmune and immunodeficiency stages).
摘要
对30例确诊的多发性硬化症患者进行了临床免疫学联合研究。讨论了通过流式细胞术和单克隆抗体评估T淋巴细胞亚群的结果；对PHA、PWM和Con A的增殖反应，以及PHA与自身血清的增殖反应；含白细胞介素-2物质的合成和接受情况。提出了免疫病理过程呈周期性的假说（自身免疫和免疫缺陷阶段）。
相似文献
1
[Characteristics of cellular immunity in multiple sclerosis].[多发性硬化症中的细胞免疫特征]
Zh Nevropatol Psikhiatr Im S S Korsakova. 1989;89(2):35-41.
2
[Functional properties of T-lymphocytes in patients with multiple sclerosis].[多发性硬化症患者T淋巴细胞的功能特性]
Zh Nevropatol Psikhiatr Im S S Korsakova. 1989;89(7):19-23.
3
[Indicators of cellular immunity in patients with multiple sclerosis].[多发性硬化症患者的细胞免疫指标]
Zh Nevropatol Psikhiatr Im S S Korsakova. 1992;92(2):12-4.
4
Cell-mediated immunodeficiency in Down's syndrome: normal IL-2 production but inverted ratio of T cell subsets.唐氏综合征中的细胞介导免疫缺陷：白细胞介素-2产生正常，但T细胞亚群比例倒置。
Clin Exp Immunol. 1984 Feb;55(2):257-63.
5
6
[Study of cellular immunity and the opioid peptide system in patients with multiple sclerosis].[多发性硬化症患者的细胞免疫与阿片肽系统研究]
Zh Nevropatol Psikhiatr Im S S Korsakova. 1990;90(2):19-24.
7
Reduction of circulating suppressor inducer T lymphocytes in the exacerbation phase of remitting-relapse multiple sclerosis.复发缓解型多发性硬化症加重期循环抑制诱导性T淋巴细胞数量减少。
Riv Neurol. 1987 May-Jun;57(3):159-62.
8
[Behavior of T lymphocytes, T helper and T suppressor, in multiple sclerosis. Preliminary report].
Rev Paul Med. 1984 Jul-Aug;102(4):181-3.
9
Suppressor T-lymphocytes in multiple sclerosis: analysis of patients with acute relapsing and chronic progressive disease.多发性硬化症中的抑制性T淋巴细胞：急性复发型和慢性进展型疾病患者的分析
Ann Neurol. 1983 Oct;14(4):445-9. doi: 10.1002/ana.410140408.
10
A longitudinal study of T cell subset surface antigen expression in multiple sclerosis.
Prog Clin Biol Res. 1984;146:119-24.
Zotero 插件