Holm S, Andersson Y, Gothefors L, Lindberg T
Department of Paediatrics, University Hospital, Umeå, Sweden.
Acta Paediatr. 1992 Aug;81(8):585-8. doi: 10.1111/j.1651-2227.1992.tb12305.x.
We investigated the intestinal absorption of the macromolecule human alpha-lactalbumin during and after an episode of acute gastroenteritis in children. Twenty children were studied in the acute phase and 17 excreted rotavirus. Eleven children were studied again 5-8 weeks later (convalescent phase). Human alpha-lactalbumin serum concentrations in the acute phase were similar but in the convalescent phase they were significantly (p less than 0.001) higher than those in the reference children. The serum concentrations were also higher in the convalescent than in the acute phase (p = 0.021). This study suggests that there is an increased absorption of proteins from the gut into the circulation 5-8 weeks after rotavirus gastroenteritis.
我们研究了儿童急性肠胃炎发作期间及之后大分子人α-乳白蛋白的肠道吸收情况。急性期对20名儿童进行了研究,其中17名排出了轮状病毒。5 - 8周后(恢复期)对11名儿童再次进行了研究。急性期人α-乳白蛋白血清浓度相似,但恢复期血清浓度显著高于参考儿童(p<0.001)。恢复期血清浓度也高于急性期(p = 0.021)。这项研究表明,轮状病毒肠胃炎后5 - 8周,肠道对蛋白质的吸收进入循环的量有所增加。