Li R L
Haerbin Medical College Thrid Hospital, Heilogjiang.
Zhonghua Zhong Liu Za Zhi. 1992 May;14(3):213-5.
From June 1975 to June 1985, 423 patients with rectal carcinoma were randomized into 4 groups: 1. Surgery alone (S), 2. Pre-operative radiotherapy plus surgery (RS), 3. Surgery plus postoperative chemotherapy (SC), and 4. Preoperative radiotherapy plus surgery followed by postoperative chemotherapy (RSC). The 5-year survival rates of the combination groups: RS-34.4% (55/160); SC-47.5% (19/40); RSC-52.4%-(33/63) were all superior to that of S alone-28.8% (40/160). The difference between RSC and S alone was particularly significant (P less than 0.01). Further studies are warranted.
1975年6月至1985年6月，423例直肠癌患者被随机分为4组：1. 单纯手术组（S）；2. 术前放疗加手术组（RS）；3. 手术加术后化疗组（SC）；4. 术前放疗加手术并术后化疗组（RSC）。联合治疗组的5年生存率：RS组为34.4%（55/160）；SC组为47.5%（19/40）；RSC组为52.4%（33/63），均高于单纯手术组的28.8%（40/160）。RSC组与单纯手术组之间的差异尤为显著（P<0.01）。有必要进行进一步研究。
