Wang Z Y, Xu Y C, Sun Y Z, Li Y, Cui S Z, Chen W, Cui S R, Zhang D Z, Ding L
Zhonghua Zhong Liu Za Zhi. 1986 May;8(3):228-30.
The results of 128 patients with rectal cancer treated by the combination of surgery, preoperative radiotherapy and chemotherapy from June 1975 to December 1979 are reported and compared with those by operation alone. The 5 year survival rates of the different groups were: 69.5% (16/23) for radical surgery plus preoperative radiotherapy and chemotherapy (RRCG), 56% (14/25) for radical surgery plus preoperative radiotherapy, 53.8% (7/13) for radical surgery plus chemotherapy and 40% (10/25) for radical surgery alone. The 5 year survival rate of RRCG was significantly higher than that of the radical surgery alone group (P less than 0.05). The authors believe that the combination of preoperative radiotherapy, chemotherapy plus radical surgery improves the 5 year survival rate and is worthy of further study.
报告了1975年6月至1979年12月期间128例接受手术、术前放疗和化疗联合治疗的直肠癌患者的结果，并与单纯手术治疗的结果进行了比较。不同组的5年生存率分别为：根治性手术加术前放疗和化疗（RRCG）组为69.5%（16/23），根治性手术加术前放疗组为56%（14/25），根治性手术加化疗组为53.8%（7/13），单纯根治性手术组为40%（10/25）。RRCG组的5年生存率显著高于单纯根治性手术组（P＜0.05）。作者认为，术前放疗、化疗加根治性手术联合应用可提高5年生存率，值得进一步研究。
