Mandel I D
Columbia University School of Dental and Oral Surgery, New York, N.Y. 10032.
Int Dent J. 1992 Aug;42(4 Suppl 1):270-5.
Recent epidemiologic studies have confirmed the widespread presence of calculus in teenagers and adults of all ages. Among the multiple anticalculus strategies that have been proposed over the years inhibition of crystal growth has been the most attractive. Current formulations in antitartar toothpastes utilise either zinc salts or various pyrophosphate combinations. In mouthrinses three recent clinical studies have established the superiority of a formulation that contains 1 per cent soluble pyrophosphate, 0.45 per cent of the copolymer of methoxyethelene and maleic acid (Gantrez) and 0.02 per cent sodium fluoride. Three and six month studies demonstrated reductions in calculus scores of 31.7-37.7 per cent using the Volpe-Manhold scoring method. A comparative study of 1 per cent pyrophosphate rinses with and without the copolymer (Gantrez) affirmed its importance to the efficacy of the formulation (31.7 per cent vs 14.4 per cent).
近期的流行病学研究证实,牙结石在各年龄段的青少年和成年人中广泛存在。多年来提出的多种防结石策略中,抑制晶体生长最具吸引力。目前的防牙垢牙膏配方使用锌盐或各种焦磷酸盐组合。在漱口水方面,最近的三项临床研究证实了一种配方的优越性,该配方含有1%的可溶性焦磷酸盐、0.45%的甲氧基乙烯与马来酸的共聚物(甘泰)和0.02%的氟化钠。使用沃尔普-曼霍尔德评分法进行的为期三个月和六个月的研究表明,牙结石评分降低了31.7%-37.7%。一项对含1%焦磷酸盐漱口水添加或不添加共聚物(甘泰)的对比研究证实了其对配方疗效的重要性(分别为31.7%和14.4%)。