Triratana T, Kietprajuk C, Banditsing P, Kraiwaphan P
Department of Oral Pathology, Mahidol University School of Dentistry, Bangkok.
J Clin Dent. 1991;3 Suppl B:B23-5.
A three-month, double-blind, parallel clinical study was conducted to evaluate the effects of three dentifrices on supragingival calculus formation. The products tested were a pyrophosphate/Gantrez copolymer, silica based dentifrice containing 0.243% sodium fluoride, a zinc citrate dentifrice containing 1.2% sodium monofluorophosphate in an alumina abrasive system, and a sodium fluoride/silica based placebo dentifrice. Using baseline Volpe-Manhold calculus scores, 150 Thai elementary school children in Chonburi Province were stratified into three balanced groups. All children then received a whole mouth oral prophylaxis and were randomly assigned one of the three test dentifrices. The children used only their assigned dentifrice for the next three months. At the end of three months, the study dentifrice containing pyrophosphate/copolymer reduced supragingival calculus deposits by 35% compared to the placebo dentifrice. This reduction was statistically significant at p less than .01. The pyrophosphate/copolymer dentifrice was also significantly better than the zinc citrate dentifrice at the p less than .01 level in reducing calculus scores. The zinc citrate dentifrice scores were not found to be significantly different from the placebo dentifrice scores on calculus reduction.
开展了一项为期三个月的双盲平行临床研究，以评估三种牙膏对龈上牙石形成的影响。所测试的产品分别是一种焦磷酸盐/甘特里兹共聚物、含0.243%氟化钠的二氧化硅基牙膏、在氧化铝研磨体系中含1.2%单氟磷酸钠的柠檬酸锌牙膏，以及一种氟化钠/二氧化硅基安慰剂牙膏。利用基线Volpe-Manhold牙石评分，春武里府的150名泰国小学生被分为三个均衡的组。所有儿童随后接受了全口口腔预防治疗，并被随机分配使用三种测试牙膏中的一种。在接下来的三个月里，孩子们只使用分配给他们的牙膏。三个月结束时，与安慰剂牙膏相比，含焦磷酸盐/共聚物的研究用牙膏使龈上牙石沉积物减少了35%。这种减少在p值小于0.01时具有统计学意义。在降低牙石评分方面，焦磷酸盐/共聚物牙膏在p值小于0.01水平时也显著优于柠檬酸锌牙膏。未发现柠檬酸锌牙膏在减少牙石方面的评分与安慰剂牙膏评分有显著差异。
