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[模拟主动脉夹层动脉瘤的肺癌]

[Lung cancer simulating dissecting aneurysm of the aorta].

作者信息

Sarnowski W, Sarnowska Z, Paluszkiewicz L, Kwinecki P, Sosnowski P, Młynarczyk W

机构信息

Z Kliniki Kardio-Torakochirurgii I.K.AM w Posnaniu.

出版信息

Kardiol Pol. 1992 Jul;37(7):22-4.

PMID:1328741
Abstract

The report analyzes a rare case of lung cancer presenting as a dissecting aortic aneurysm. A 59-year-old patient was admitted to the Department of Cardiosurgery of the Institute of Cardiology, Poznań Medical School, with a preliminary diagnosis of dissecting aneurysm of ascending aorta. The patient had hypertension treated for 5 years and 3 year history of retrosternal pains. He had smoked 20 cigarettes daily for 20 years. On admission a strong chest pain radiating into the ++inter-scapular region was reported. After two days the radiation extended into the lumbosacral area. Blood pressure was 180/100 mmHg. After 7 days paresis of the lower extremities occurred. Ecg showed only hypertrophy of the left ventricle. Chest X-ray revealed dilatation of the mediastinum and enlargement of the lungs, without focal changes. Echo (M + 2D + Doppler) suggested aortic wall dissection in the ascending part and the arch. The DSA examination did not reveal the dissection, which in turn suggested mediastinal tumor. TC presented an extensive infiltration of the upper-medial part of the right lung and invaded right mediastinum. The final diagnosis, oat cell carcinoma, was established after the histopathological analysis of a biopsy specimen taken in the course of bronchoscopy. The patient died at home after two months of oncological treatment. Autopsy was not performed. In spite of considerable progress of the diagnostic technics both dissecting aortic aneurysm and lung cancer still present a very difficult clinical problem.

摘要

该报告分析了一例罕见的以主动脉夹层动脉瘤形式出现的肺癌病例。一名59岁患者因初步诊断为升主动脉夹层动脉瘤入住波兹南医科大学心脏病学研究所心脏外科。该患者有5年高血压病史及3年胸骨后疼痛病史。他每天吸烟20支,共20年。入院时报告有强烈胸痛放射至肩胛间区。两天后放射痛扩展至腰骶部。血压为180/100 mmHg。7天后出现下肢麻痹。心电图仅显示左心室肥厚。胸部X线显示纵隔增宽和肺部增大,无局灶性改变。超声心动图(M+2D+多普勒)提示升主动脉和主动脉弓部的主动脉壁夹层。数字减影血管造影(DSA)检查未发现夹层,提示纵隔肿瘤。胸部CT显示右肺上内侧广泛浸润并侵犯右纵隔。经支气管镜活检标本的组织病理学分析后确诊为燕麦细胞癌。该患者在接受肿瘤治疗两个月后在家中死亡。未进行尸检。尽管诊断技术有了很大进展,但主动脉夹层动脉瘤和肺癌仍然是非常棘手的临床问题。

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