Ng M, Linthicum F H
House Ear Institute, University of Southern California School of Medicine, Los Angeles.
Laryngoscope. 1992 Oct;102(10):1097-102. doi: 10.1288/00005537-199210000-00002.
Silastic sheeting is used to restore a mucosally lined middle ear space and to prevent mucosal adhesions between the medial surface of the tympanic membrane and the promontory after surgical procedures involving the removal of middle ear mucosa. To determine the long-term (1.2 to 21.2 years) effects of Silastic sheeting in the middle ear, six temporal bones from patients with permanent Silastic sheeting in the middle ear cavity after single-stage tympanoplasty were examined. In all six bones, no histologic evidence of foreign body reaction, rejection, or chronic inflammation in the middle ear surrounding the silicone sheeting was observed. Furthermore, the middle ear space was lined by normal-appearing, continuous middle ear mucosa. In four temporal bones, there was no evidence of significant submucosal fibrosis. In two bones, significant submucosal fibrosis was attributable to concurrent middle ear disease rather than to the presence of the silicone. It is concluded that Silastic sheeting in the middle ear after single-stage procedures may prevent adhesions between mucosal surfaces. Given eustachian tube function, Silastic promotes a mucosally lined, aerated middle ear cavity without apparent foreign body reaction, rejection, or chronic inflammatory response.
硅橡胶片用于恢复有黏膜衬里的中耳腔，并在涉及切除中耳黏膜的手术后防止鼓膜内表面与岬之间的黏膜粘连。为了确定硅橡胶片在中耳的长期（1.2至21.2年）效果，对6例在一期鼓室成形术后中耳腔有永久性硅橡胶片的患者的颞骨进行了检查。在所有6块颞骨中，未观察到围绕硅橡胶片的中耳有异物反应、排斥或慢性炎症的组织学证据。此外，中耳腔由外观正常、连续的中耳黏膜衬里。在4块颞骨中，没有明显的黏膜下纤维化证据。在2块颞骨中，明显的黏膜下纤维化归因于并发的中耳疾病，而非硅橡胶的存在。得出的结论是，一期手术后中耳内的硅橡胶片可能会防止黏膜表面之间的粘连。在咽鼓管功能正常的情况下，硅橡胶可促进有黏膜衬里、通气的中耳腔形成，且无明显的异物反应、排斥或慢性炎症反应。
