Gamoletti R, Zini C, Sanna M, Bellomi A
ORL J Otorhinolaryngol Relat Spec. 1982;44(6):310-7. doi: 10.1159/000275610.
The surgeon's attitude towards the diseased middle ear mucosa during intact canal wall tympanoplasty has remained a controversial problem. Our approach consists of the complete removal of the irreversibly diseased mucosal lining. A planned staged operation has been carried out in most cases of tympanoplasty with the use of Silastic sheeting. At the time of the second operation, the middle ear and mastoid process appear to be lined by the regenerated mucosa and pneumatized. 54 mucosal biopsies taken during the second stage of the operation showed a normal flat, cuboidal and pseudostratified ciliated epithelium with functional features (secretory granules, microvilli and cilia). It is concluded that the diseased middle ear mucosa can be removed whenever necessary during staged closed-tympanoplasty operations because under the Silastic sheeting the mucosa will be regenerated within 12 months.
在完整外耳道壁鼓室成形术中，外科医生对病变中耳黏膜的态度一直是个有争议的问题。我们的方法是彻底清除不可逆病变的黏膜内衬。在大多数鼓室成形术病例中，我们使用硅橡胶片进行了计划性分期手术。在第二次手术时，中耳和乳突似乎被再生的黏膜覆盖并有气腔形成。在手术第二阶段采集的54份黏膜活检样本显示，有具有功能特征（分泌颗粒、微绒毛和纤毛）的正常扁平、立方和假复层纤毛上皮。结论是，在分期闭合式鼓室成形术中，必要时可切除病变中耳黏膜，因为在硅橡胶片下，黏膜将在12个月内再生。
