[Disorders of sorbitol and myoinositol metabolism and the activity of sodium, potassium ATPase in the pathogenesis of peripheral neuropathy in patients with diabetes mellitus].

Authors discussed the actual status of information concerning the disturbances in function: 1) of sorbitol biochemical pathway, 2) myoinositol metabolism and 3) activity of Na(+)-K(+)-ATP-ase related to diabetic hyperglycemia. Preliminary data on the possible benefit of aldo-reductase inhibitors therapy are also presented.