Liao K K, Chang M H, Wang S
Neurological Institute, Veterans General Hospital-Taipei, Taiwan, R.O.C.
Zhonghua Yi Xue Za Zhi (Taipei). 1992 Sep;50(3):203-7.
Nine patients complaining of distal paresthesia were found to have spinal cord lesions with no evidence of peripheral nerve disease. This pattern may be due to central nervous system dysfunction, with a lesion being intramedullary or extramedullary. The sensory deficits were initially asymmetric. Paresthesias could originate from the hands and progress to the stocking-glove pattern. It was usually more severe in hands than in feet. The abnormal somatosensory evoked potentials, found in all patients, indicated a lesion involving the posterior column, a site supposed to be the pathologic basis of paresthesia. As hands and feet have relatively large somatotopic representation in the posterior column of the cervical cord, the paresthesia tends to localize over distal portions of extremities.
9名主诉远端感觉异常的患者被发现有脊髓病变，无周围神经疾病证据。这种模式可能是由于中枢神经系统功能障碍，病变可能位于髓内或髓外。感觉障碍最初是不对称的。感觉异常可起源于手部，并发展为手套-袜套样分布。通常手部比足部更严重。所有患者均发现异常体感诱发电位，提示病变累及后柱，该部位被认为是感觉异常的病理基础。由于手和脚在颈髓后柱中有相对较大的躯体定位代表区，感觉异常往往定位于四肢远端。
