Arutiunian N A, Savchenko O N, Proĭmina F I, Sekretareva E V
Fiziol Zh SSSR Im I M Sechenova. 1992 Feb;78(2):110-7.
In rats with preserved ovaries, both in normal and in neonatally androgenized, the activity of enzymes kreatinphosphokinase and peroxidase cannot serve as the marker of the estradiol effect upon the uterus. In ovariectomised animals, the dynamics of activity of these enzymes corresponds to uterotropic responses to estradiol. but not to the dynamics of hormone receptor complexes. The data obtained makes doubtful the participation of the hormone receptor complexes in realisation of the estrogens effect upon the uterus.
在保留卵巢的大鼠中，无论是正常大鼠还是新生期雄激素化的大鼠，肌酸磷酸激酶和过氧化物酶的活性都不能作为雌二醇对子宫作用的标志物。在去卵巢动物中，这些酶活性的动态变化与子宫对雌二醇的促生长反应相对应，但与激素受体复合物的动态变化不对应。所获得的数据使人怀疑激素受体复合物是否参与雌激素对子宫作用的实现。
