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使用涤纶/聚氨酯复合材料进行颅面轮廓缺损重建:一种用于骨诱导制造和应用的异体塑料托盘。

Craniofacial contour defect reconstruction with a dacron/urethane composite: an alloplastic tray for bone induction fabrication and application.

作者信息

Leake D L, Habal M B

出版信息

J Biomed Mater Res. 1976 Jul;10(4):555-60. doi: 10.1002/jbm.820100412.

Abstract

An alloplastic tray made of poly(ethylene terephthalate) cloth mesh and poly(ether urethane) used in conjunction with cancellous bone-chip grafts is the basis for this new method of reconstructing facial osseous contour defects. The tray can be prefabricated in quantity and at low cost for standard defects, such as discontinuity defects of the mandible or for chin augmentation. It can be custom-fabricated for specific defects in individual patients as, for example, gunshot wounds to the forehead. The materials were chosen because of their known histocompatibility, the ease of fabrication, and because the materials can be molded to form esthetic contours. The can be easily modified at the time of surgery. Sterilization is by autoclaving. Initial studied were undertaken in mongrel dogs where mandibular discontinuity defects in the range of 2-4 cm were reconstructed. In man, the technique has been used to reconstruct discontinuity defects of the mandible ranging in size from 1.5-12 cm in 16 patients. Atrophic mandibular alveolar ridges have been augmented using this technique in 7 patients, thus providing an adequate alveolar ridge for dentures. Two patients with defects of the skull secondary to gunshot wounds have had frontal bone restoration using this method. Reconstructions of the ear, the chin, and the orbital floor are currently being evaluated. This technique overcomes many problems of esthetic contour reconstruction and combines the use of autogenous cancellous particulate bone and a tissue-compatible synthetic composite material.

摘要

一种由聚对苯二甲酸乙二酯布网和聚醚聚氨酯制成的异质托盘,与松质骨屑移植联合使用,是这种重建面部骨轮廓缺损新方法的基础。该托盘可针对标准缺损(如下颌骨连续性缺损或隆颏)进行批量预制且成本低廉。它也可为个体患者的特定缺损(如前额枪伤)定制。选择这些材料是因为它们已知的组织相容性、易于制造,且这些材料可模塑形成美观的轮廓。在手术时可轻松对其进行修改。通过高压灭菌进行消毒。最初在杂种犬身上进行研究,重建了2 - 4厘米范围的下颌骨连续性缺损。在人类中,该技术已用于重建16例患者大小为1.5 - 12厘米的下颌骨连续性缺损。7例患者使用该技术增大了萎缩的下颌牙槽嵴,从而为义齿提供了足够的牙槽嵴。2例因枪伤导致颅骨缺损的患者使用该方法进行了额骨修复。目前正在评估耳部、颏部和眶底的重建情况。该技术克服了美学轮廓重建的许多问题,并结合了自体松质颗粒骨和组织相容性合成复合材料的使用。

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