Leake D, Habal M, Maniscalco J, Freeman S
J Biomed Mater Res. 1978 Jan;12(1):83-7. doi: 10.1002/jbm.820120108.
The purpose of this report is to present out 5-year experience in reconstructing large bony defects in the cranial vault of 16 patients. The method employs an alloplastic implant device made of elastomer-coated cloth mesh, used in conjunction with bone grafting [D. L. Leake and M. Habal, J. Biomed. Mater. Res., 10, 555 (1976)]. The cranial defects ranged in size from 6 X 6 cm to 15 X 17 cm. The defects were in the frontal, temporoparietal, and occipital regions. Particularly challenging was the frontal-orbital region involving the superciliary ridges. The alloplastic implant provides controlled contour of the bone graft material while providing strength and stability during healing. The implant has adequate but not complete ridigity, allowing adaptability inthe operating room. The elastomer used is a polyetherurethane. Any biocompatible cloth mesh can be used, but Dacron [poly(ethylene terephthalate)] was chosen because of its extensive implant history. Contrasted with reconstruction using only bone, where as many as half of the cases had uneveness and were found to be anesthetically unsatisfactory, the technique described here has resulted in aesthetically excellent results and an intact neurocranium in the 16 patients studied thus far.
本报告旨在介绍我们在16例患者的颅顶大骨缺损重建方面的5年经验。该方法采用一种由涂有弹性体的布网制成的异体植入装置,并与骨移植联合使用[D. L. 利克和M. 哈巴尔,《生物医学材料研究杂志》,10, 555 (1976)]。颅骨缺损大小从6×6厘米到15×17厘米不等。缺损位于额部、颞顶部和枕部区域。特别具有挑战性的是涉及眉嵴的额眶区域。异体植入物在愈合过程中为骨移植材料提供可控的轮廓,同时提供强度和稳定性。该植入物具有足够但不完全的刚性,在手术室中具有适应性。所使用的弹性体是一种聚醚聚氨酯。任何生物相容性布网都可以使用,但由于涤纶[聚对苯二甲酸乙二酯]有广泛的植入历史,所以选择了它。与仅使用骨进行重建相比,在仅使用骨重建的情况下,多达一半的病例存在不平整且在美学上不令人满意,而此处描述的技术在目前所研究的16例患者中已产生了美学效果极佳且神经颅骨完整的结果。