Nakamura T, Shimizu Y, Mizuno H, Hitomi S, Kitano M, Matsunobe S
Department of Physiological Artificial Organs, Kyoto University, Japan.
Nihon Kyobu Geka Gakkai Zasshi. 1992 Oct;40(10):1828-31.
Bioabsorbable PGA non-woven fabric sheets were used to treat 103 patients who underwent pulmonary surgery in three hospitals, and their handleability, applicability, drainage time after surgery and subsequent side effects were studied. For suture reinforcement, these sheets showed satisfactory handleability, applicability and effectiveness for hemostasis and prevention of air leakage at the suture sites. Since this material has good compatibility with fibrin glue, use of these two materials in combination reduced both the operation time and postoperative drainage period. For small fistula and pleural defects, attachment of the sheets with fibrin glue to create an artificial pleura was sufficient for prevention air leakage without suturing. No side effects or complications were observed, and the postoperative courses of all 103 patients were uneventful. These findings suggest that PGA sheets are acceptable for suture reinforcement in the pulmonary surgery, and that when used with fibrin glue, can simplify surgery for emphysematous lung disease and shorten the period of postoperative air leakage.
采用生物可吸收聚乙醇酸无纺布片对三家医院的103例行肺手术患者进行治疗，并对其可操作性、适用性、术后引流时间及后续副作用进行研究。对于缝合加固，这些片材在可操作性、适用性以及止血和预防缝合部位漏气方面显示出令人满意的效果。由于这种材料与纤维蛋白胶具有良好的相容性，联合使用这两种材料可缩短手术时间和术后引流时间。对于小瘘口和胸膜缺损，用纤维蛋白胶粘贴片材以形成人工胸膜足以预防漏气，无需缝合。未观察到副作用或并发症，103例患者术后病程均顺利。这些结果表明，聚乙醇酸片材可用于肺手术中的缝合加固，与纤维蛋白胶联合使用时，可简化肺气肿性肺疾病的手术并缩短术后漏气时间。
