Evidence for tachykinin NK-2B-like receptors in guinea-pig alveolar macrophages.
作者信息
Brunelleschi S, Ceni E, Fantozzi R, Maggi C A
机构信息
Dept. Pharmacology, Univ. Florence, Firenze, Italy.
出版信息
Life Sci. 1992;51(20):PL177-81. doi: 10.1016/0024-3205(92)90626-z.
PMID:1331635
Abstract
Mammalian tachykinins dose-dependently activate guinea-pig alveolar macrophages, by interacting with tachykinin NK-2 receptors, mainly. By evaluating the effects of different NK-2 tachykinin receptor antagonists, we now provide evidence that tachykinin NK-2 receptors in guinea-pig alveolar macrophages meet the pharmacological criteria used to define the NK-2B subtype.
摘要
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