Misiewicz A, Trzcionka-Bera D, Stoch K
VI Katedry i Kliniki Chorób Wewnetrznych Sl. AM, Katowicach.
Pol Tyg Lek. 1992;47(5-6):129-30.
Acid phosphatase activity examinations and nitrotetrazolium blue reduction test after latex stimulation in peripheral blood neutrophils were performed in the group of 32 coking plant workers. Reference group consisted of 150 men not exposed to any toxic substances. Neutrophils of coking plant workers, comparing with the reference group, revealed decreased activity of acid phosphatase and impaired reduction of nitrotetrazolium blue after latex stimulation. The results suggest the possibility of toxic influence of coking plant environment on the lysosomal enzymes and oxygen-dependent metabolism of neutrophils what subsequently may diminish bactericidal powers.
对32名焦化厂工人进行了外周血中性粒细胞乳胶刺激后的酸性磷酸酶活性检测和硝基四氮唑蓝还原试验。对照组由150名未接触任何有毒物质的男性组成。与对照组相比，焦化厂工人的中性粒细胞在乳胶刺激后酸性磷酸酶活性降低，硝基四氮唑蓝还原受损。结果表明，焦化厂环境可能对中性粒细胞的溶酶体酶和氧依赖性代谢产生毒性影响，进而可能削弱杀菌能力。
