Logullo F, Censori B, Danni M, Del Pesce M, Di Bella P, Provinciali L
Istituto delle Malattie del Sistema Nervoso, Università degli Studi, Ancona, Italy.
Electromyogr Clin Neurophysiol. 1992 Oct-Nov;32(10-11):515-20.
Peripheral neuropathy was investigated in thirty-one patients with myotonic dystrophy (MyD) and sixteen relatives. Using standard electrophysiological criteria, a sensorimotor axonal peripheral neuropathy was found in 14 MyD cases (45%) and not in unaffected first-degree relatives. The whole group of the MyD patients showed significant impairment of mean motor and sensory conduction values, compared with controls. The presence of polyneuropathy was correlated with the patients' age and the severity and duration of the clinical manifestations of MyD.
对31例强直性肌营养不良（MyD）患者及16名亲属进行了周围神经病变的研究。采用标准电生理标准，在14例MyD患者（45%）中发现了感觉运动轴索性周围神经病变，而在未受影响的一级亲属中未发现。与对照组相比，MyD患者全组的平均运动和感觉传导值均有显著损害。多神经病变的存在与患者年龄以及MyD临床表现的严重程度和病程相关。
