Jamjoom A, al-Abedeen Jamjoom Z, al-Hedaithy S, Jamali A, Malabarey T
Division of Neurosurgery, King Khalid University Hospital, Riyadh, Saudi Arabia.
Br J Neurosurg. 1992;6(5):501-4. doi: 10.3109/02688699208995043.
A unique case of Candida albicans ventriculitis and hydrocephalus in the absence of any evidence of systemic candidiasis or immunosuppression is reported. Initial treatment with CSF shunting and intravenous antimycotic therapy appeared to have eradicated the infection. Recurrence occurred 5 months after discharge and this was treated by intravenous and intrathecal antimycotic therapy in addition to removal of the shunt system, external ventricular drainage and then replacement of the shunt. A concomitant pyogenic brain abscess responded to burrhole aspiration and antibiotics. The role of mannan antigen monitoring is discussed.
报道了一例独特的白色念珠菌性脑室炎和脑积水病例，该病例未出现任何系统性念珠菌病或免疫抑制的证据。最初采用脑脊液分流术和静脉注射抗真菌治疗，似乎根除了感染。出院5个月后复发，除移除分流系统、进行外部脑室引流然后更换分流管外，还通过静脉和鞘内抗真菌治疗进行处理。同时存在的化脓性脑脓肿经钻孔抽吸和抗生素治疗后好转。文中讨论了甘露聚糖抗原监测的作用。
