Tajima M, Yazawa T, Hagiwara K, Kurosawa T, Takahashi K
Department of Veterinary Internal Medicine, Rakuno Gakuen University, Ebetsu, Japan.
Zentralbl Veterinarmed A. 1992 Oct;39(8):616-20. doi: 10.1111/j.1439-0442.1992.tb00225.x.
Four Japanese black cattle and four Holstein-Friesian cows were diagnosed with diabetes mellitus. Based on intravenous glucose tolerance tests, all these animals were believed to be insulin-dependent diabetics. Moreover, bovine viral diarrhea-mucosal disease (BVD-MD) virus was isolated and mucosal lesions and diarrhea were recognized in all cases. There was no genetic relation among the affected cattle. The breeding places of these cattle were different to each other. Therefore, it is suggested that BVD-MD virus induced the diabetes mellitus.
四头日本黑牛和四头荷斯坦-弗里生奶牛被诊断患有糖尿病。基于静脉葡萄糖耐量试验，所有这些动物被认为是胰岛素依赖型糖尿病患者。此外，分离出了牛病毒性腹泻-黏膜病（BVD-MD）病毒，并且在所有病例中都发现了黏膜损伤和腹泻。患病牛之间没有遗传关系。这些牛的饲养地彼此不同。因此，提示BVD-MD病毒诱发了糖尿病。
