Ringdén O, Groth C G, Lundgren G, Möller E
Scand J Urol Nephrol. 1975(29 Suppl):15-8.
In 45 recipients of intrafamilial kidney transplants, the one year survival of sibling grafts was 95% and of parental grafts 71%. HL-A compatible grafts had a one year survival of 94% compared to 75% of HL-A incompatible grafts. At the same time, the survival of MLC compatible grafts was 100% and that of MLC incompatible grafts 74%. These differences are not statistically significant but suggest a prognostic importance of MLC, as well as HL-A matching. MLC compatibility might be more crucial than HL-A compatibility. MLC test performed after transplantation when the recipients were on maintenance immunosuppressive therapy, did not show reduced reactivity of recipient lymphocytes as compared to tests performed prior to surgery.
在45例接受家族内肾移植的患者中，同胞供肾移植的1年存活率为95%，亲体供肾移植的1年存活率为71%。HL-A配型相合的移植肾1年存活率为94%，而HL-A配型不相合的移植肾为75%。同时，混合淋巴细胞培养（MLC）配型相合的移植肾存活率为100%，MLC配型不相合的移植肾存活率为74%。这些差异无统计学意义，但提示MLC以及HL-A配型对预后具有重要性。MLC配型可能比HL-A配型更为关键。在接受者进行维持性免疫抑制治疗时移植后进行的MLC检测显示，与术前检测相比，接受者淋巴细胞的反应性并未降低。
