ABO-Ii系统中的自身抗体（作者译）
[Autoantibodies in the ABO-Ii-system (author's transl)].
作者信息
Graninger W
出版信息
Z Immunitatsforsch Exp Klin Immunol. 1975 Nov;150(5):389-402.
Nine cases of autoantibodies in the ABO-system, found by routine investigations, showed the following specificities by agglutination, absorption, and elution techniques: 5 anti-AI, 2 anti-(not-I)-A, I anti-BI and 1 anti-HI. Neutralization experiments by blood group substances revealed heterogeneity among the 5 anti-AI-cases. This is interpreted by different antibody specificities directed against I-antigen components. The relations between the ABO- and Ii-systems are discussed. The occurrence of these antibodies is attributed to oligosaccharides, which are common to both antigen systems. The etiology remains unknown.
通过常规检查发现的9例ABO系统自身抗体，经凝集、吸收和洗脱技术检测显示出以下特异性：5例抗-AI、2例抗-（非I）-A、1例抗-BI和1例抗-HI。血型物质的中和试验揭示了5例抗-AI病例之间的异质性。这可以通过针对I抗原成分的不同抗体特异性来解释。讨论了ABO系统和Ii系统之间的关系。这些抗体的出现归因于两种抗原系统共有的寡糖。病因仍然不明。
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