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Streptolydigin, a new antimicrobial antibiotic. II. Isolation and characterization.

作者信息

CRUM G F, DEVRIES W H, EBLE T E, LARGE C M, SHELL J W

出版信息

Antibiot Annu. 1955;3:893-6.

PMID:13355382
Abstract
摘要

相似文献

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Streptolydigin, a new antimicrobial antibiotic. II. Isolation and characterization.
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Single-molecule studies reveal the off-pathway early paused state intermediates as a target of streptolydigin inhibition of RNA polymerase and its dramatic enhancement by Gre factors.单分子研究揭示了偏离途径的早期暂停状态中间体是链霉溶菌素抑制RNA聚合酶的靶点,以及Gre因子对其的显著增强作用。
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手性四氢吡咯酸的合成:由L-苯丙氨酸甲酯盐酸盐制备()-5-苄基吡咯烷-2,4-二酮。
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Chemical synthesis enables biochemical and antibacterial evaluation of streptolydigin antibiotics.化学合成使链霉溶菌素抗生素的生化和抗菌评估成为可能。
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