Grigorjev P A, Schlegel R, Gräfe U
Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino na Oke, Moscow region.
Pharmazie. 1992 Sep;47(9):707-9.
By the use of an artificial lipid membrane model we have shown that the antibiotic oxazolomycin (Streptomyces albus) is an effective protonophore at pH < 7.0 but conveys both protons and monovalent cations such as potassium at pH > 7.5 as a passive carrier. The ionophoric properties are suggested to be correlated with its antibacterial, antiviral, and cytotoxic activities.
