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微体与肝细胞中线粒体再生的问题。

Microbodies and the problem of mitochondrial regeneration in liver cells.

作者信息

BERNHARD W, ROUILLER C

出版信息

J Biophys Biochem Cytol. 1956 Jul 25;2(4 Suppl):355-60. doi: 10.1083/jcb.2.4.355.

Abstract

The cytoplasm of the hepatic cell contains, besides the well known organelles, microbodies, characterized by a single membrane, a finely granular matrix, and average dimensions below those of mitochondria. Microbodies, rare in normal cells, become more numerous in regenerative livers and in various pathological conditions. In these cases, they either evolve towards degenerative forms or else show structural modifications corresponding to transitional forms between them and mitochondria. This suggests to us that the microbodies can be precursors of mitochondria.

摘要

肝细胞的细胞质中,除了众所周知的细胞器外,还有微体。微体由单层膜包被,基质呈细颗粒状,平均尺寸小于线粒体。微体在正常细胞中很少见,在再生肝和各种病理状态下数量增多。在这些情况下,它们要么演变成退化形式,要么表现出与它们和线粒体之间过渡形式相对应的结构改变。这向我们表明,微体可能是线粒体的前体。

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