Finnegan D J
Institute of Molecular Biology, Edinburgh University, Scotland.
Curr Opin Genet Dev. 1992 Dec;2(6):861-7. doi: 10.1016/s0959-437x(05)80108-x.
Transposable elements comprise a major fraction of eukaryotic genomes. They are studied both because of their intrinsic biological interest and because they can be exploited as valuable research tools. Many interesting papers dealing with various aspects of the biology of these elements have been published during the past year and a number of new elements have been reported. Four areas in which particularly valuable contributions have been made are the mechanisms of transposition, the regulation of transposition, the use of transposable elements as research tools, and the biological function of transposable elements.
转座元件构成了真核生物基因组的主要部分。对它们进行研究,既是出于其内在的生物学研究价值,也是因为它们可作为有价值的研究工具加以利用。在过去一年里,发表了许多涉及这些元件生物学各个方面的有趣论文,还报道了一些新元件。做出了特别有价值贡献的四个领域是转座机制、转座调控、转座元件作为研究工具的应用以及转座元件的生物学功能。