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多氯二苯并对二恶英、二苯并呋喃和联苯对人类健康及环境的影响，特别强调毒性当量因子概念的应用。

Impact of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls on human and environmental health, with special emphasis on application of the toxic equivalency factor concept.

作者信息

Ahlborg U G, Brouwer A, Fingerhut M A, Jacobson J L, Jacobson S W, Kennedy S W, Kettrup A A, Koeman J H, Poiger H, Rappe C

机构信息

Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden.

出版信息

Eur J Pharmacol. 1992 Dec 1;228(4):179-99. doi: 10.1016/0926-6917(92)90029-c.

DOI:10.1016/0926-6917(92)90029-c
PMID:1335882
Abstract

A scientific evaluation was made of the mechanisms of action of polychlorinated dibenzo-p-dioxins, dibenzofurans and biphenyls. Distinction is made between the aryl-hydrocarbon (Ah) receptor-mediated and non-Ah receptor-mediated toxic responses. Special attention is paid to the applicability of the toxic equivalency factor (TEF) concept.

摘要

对多氯二苯并对二恶英、二苯并呋喃和联苯的作用机制进行了科学评估。区分了芳烃（Ah）受体介导的和非Ah受体介导的毒性反应。特别关注了毒性当量因子（TEF）概念的适用性。

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