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一项针对纽约州三个大都市区空气污染与呼吸道疾病住院情况的多年研究:1988年和1989年夏季的结果

A multi-year study of air pollution and respiratory hospital admissions in three New York State metropolitan areas: results for 1988 and 1989 summers.

作者信息

Thurston G D, Ito K, Kinney P L, Lippmann M

机构信息

Nelson Institute of Environmental Medicine, NYU Medical Center, Tuxedo 10987.

出版信息

J Expo Anal Environ Epidemiol. 1992 Oct-Dec;2(4):429-50.

PMID:1336418
Abstract

As part of a multi-year study of air pollution and respiratory hospital admissions in the Buffalo, Albany, and New York City, New York, metropolitan areas, filter samples were collected daily at suburban air monitoring sites and analyzed for their content of particulate phase aerosol strong acidity (i.e., hydrogen ion, H+) and sulfate (SO4 = ). In addition, daily hospital admissions for respiratory causes, other community air pollutant measurements (e.g., ozone, O3), and meteorological data (e.g., temperature) were also obtained for these metropolitan areas. The summer months (June-August) were selected for analysis because that is when the highest H+ (and O3) are usually experienced at these sites, and because these months are rarely complicated by other major influences (e.g., high pollen counts). Thus, any pollution-admissions relationships were expected to be most clearly discernible in this season. Prior to the health effects analysis, the summer admissions and environmental data were first detrended to eliminate long-wave autocorrelations, and day-of-week effects were removed via regression. Cross-correlations of the filtered 1988 and 1989 admissions and environmental data revealed strong associations between elevated summer haze pollution (i.e., H+, SO4 =, and O3) and increased total respiratory and asthma admissions on the same day and/or on subsequent days in Buffalo and New York City, especially during the summer of 1988 (when pollution levels were more extreme). Regression analyses indicated that the pollution-admissions associations remained significant (p < 0.05) even after the simultaneous inclusion of lagged daily maximum temperature. Mean effects calculations for these cities indicated that summertime haze can play a significant role in the occurrence of respiratory admissions in that season: accounting for an average 6 to 24% of 1988 Buffalo and NYC asthma admissions (depending on the pollutant index employed). O3 consistently had the highest mean effects estimates. Relative risk (RR) calculations indicated that the risk of admission for asthma was increased by a factor of 1.19 to 1.43 in these cities on maximum 1988 summertime pollution days, with H+ consistently having the highest RR estimates. These results are consistent with the hypothesis that ambient acid aerosol peaks (e.g., H+ > or = 100 nmol/m3) can potentiate the respiratory disease effects of O3. Associations were weaker in the less urbanized Albany metropolitan area and in the New York City (NYC) suburbs, even though the NYC suburban O3 exposures were similar to (and the H+ concentrations may even be somewhat higher than) those in the center city.(ABSTRACT TRUNCATED AT 400 WORDS)

摘要

作为一项针对纽约州布法罗、奥尔巴尼和纽约市大都市区空气污染与呼吸道疾病住院情况的多年研究的一部分,研究人员每天在郊区空气监测点采集过滤样本,并分析其中颗粒相气溶胶强酸度(即氢离子,H⁺)和硫酸盐(SO₄²⁻)的含量。此外,还获取了这些大都市区因呼吸道疾病导致的每日住院人数、其他社区空气污染物测量数据(如臭氧,O₃)以及气象数据(如温度)。选择夏季月份(6月至8月)进行分析,是因为这是这些监测点通常H⁺(和O₃)浓度最高的时期,且这些月份很少受到其他主要因素(如高花粉计数)的干扰。因此,预计在这个季节任何污染与住院人数之间的关系最为明显。在进行健康影响分析之前,先对夏季住院人数和环境数据进行去趋势处理,以消除长波自相关性,并通过回归消除一周中各天的影响。对1988年和1989年经过过滤的住院人数及环境数据进行互相关分析发现,布法罗和纽约市夏季雾霾污染加剧(即H⁺、SO₄²⁻和O₃)与当日和/或随后几天总呼吸道疾病及哮喘住院人数增加之间存在强烈关联,尤其是在1988年夏季(当时污染水平更为极端)。回归分析表明,即使同时纳入滞后的每日最高气温,污染与住院人数之间的关联仍然显著(p < 0.05)。这些城市的平均影响计算表明,夏季雾霾在该季节呼吸道疾病住院情况的发生中可能起重要作用:占1988年布法罗和纽约市哮喘住院人数的平均6%至24%(取决于所采用的污染物指数)。O₃的平均影响估计值始终最高。相对风险(RR)计算表明,在1988年夏季污染最严重的日子里,这些城市哮喘住院风险增加了1.19至1.43倍,H⁺的RR估计值始终最高。这些结果与以下假设一致:环境酸性气溶胶峰值(如H⁺≥100 nmol/m³)可增强O₃对呼吸道疾病的影响。在城市化程度较低的奥尔巴尼大都市区和纽约市郊区,这种关联较弱,尽管纽约市郊区的O₃暴露水平与市中心相似(且H⁺浓度甚至可能略高于市中心)。(摘要截选至400字)

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