Hermann G, Abdelwahab I F, Miller T T, Klein M J, Lewis M M
Department of Radiology, Mount Sinai Medical Center, CUNY, NY 10029-6574.
Br J Radiol. 1992 Jan;65(769):14-20. doi: 10.1259/0007-1285-65-769-14.
49 primary soft-tissue masses were studied by magnetic resonance imaging (MRI) in an effort to differentiate benign from malignant lesions. There were 24 benign and 25 malignant tumours. Images were evaluated for the presence of low-signal septation, changes in pattern of homogeneity, signal intensity, and margin definition and shape. 20 of the 25 malignant tumours (80%) demonstrated low-signal septation, and two of the 24 benign tumours (8%) also demonstrated this feature. Malignant tumours tended to change pattern from being homogeneous on T1-weighted images to being heterogeneous on T2-weighted images (72%). Benign tumours maintained their pattern on both sequences (67%). Only three of the 24 benign tumours (12.5%) changed from being homogeneous to heterogeneous. Our findings suggest that tumours which change pattern, from homogeneous on T1-weighted images to heterogeneous on T2-weighted images, and tumours which have low-signal septations are likely to be malignant. Moreover benign lesions tend to have well defined margins, and some benign masses have characteristic appearances that aid in their differentiation from malignant processes.
对49个原发性软组织肿块进行了磁共振成像（MRI）研究，以区分良性和恶性病变。其中有24个良性肿瘤和25个恶性肿瘤。对图像评估低信号分隔、均匀性模式变化、信号强度、边界清晰度和形状。25个恶性肿瘤中有20个（80%）显示低信号分隔，24个良性肿瘤中有2个（8%）也显示出这一特征。恶性肿瘤在T1加权图像上倾向于从均匀模式转变为T2加权图像上的不均匀模式（72%）。良性肿瘤在两个序列上均保持其模式（67%）。24个良性肿瘤中只有3个（12.5%）从均匀变为不均匀。我们的研究结果表明，在T1加权图像上从均匀模式转变为T2加权图像上不均匀模式的肿瘤以及具有低信号分隔的肿瘤可能是恶性的。此外，良性病变往往边界清晰，一些良性肿块具有有助于将它们与恶性病变区分开来的特征性表现。
