Gugenheim J, Crafa F, Iovine L, Fabiani P, Militerno G, Spampatti G, Goubaux B, Mouiel J
Unità Trapianti d'Organo, Centro Ospedaliero Universitario, St. Roch, Nizza, Francia.
Minerva Chir. 1992 Nov;47(21-22):1675-9.
Nineteen orthotopic liver transplantations (OLT) were performed in patients with hepatocellular carcinoma, between March 1988 and December 1990, in our Department. Thirteen patients (68.4%), 10 men and 3 women, mean age 48.2 +/- 2.8 years, were clear cut neoplastic disease, six patients (31.6%), 4 men and 2 women, mean age 48.6 +/- 4.2 years, were incidental tumors. Three years survival rate was 20% in clear cut neoplastic diseases (4 patients died for neoplastic recurrence) and 66% in incidental tumors. Our results demonstrate that liver transplantation for hepatobiliary malignancy is still justified, patient selection is important in predicting outcome.
1988年3月至1990年12月期间，我们科室对患有肝细胞癌的患者进行了19例原位肝移植（OLT）手术。13例患者（68.4%），10名男性和3名女性，平均年龄48.2±2.8岁，为明确的肿瘤性疾病；6例患者（31.6%），4名男性和2名女性，平均年龄48.6±4.2岁，为偶然发现的肿瘤。明确的肿瘤性疾病患者的三年生存率为20%（4例因肿瘤复发死亡），偶然发现的肿瘤患者的三年生存率为66%。我们的结果表明，肝移植治疗肝胆恶性肿瘤仍然是合理的，患者选择对于预测预后很重要。
