Levasseur P
Service de Chirurgie Thoracique et Vasculaire, Hôpital Marie-Lannelongue, Le Plessis-Robinson.
Rev Mal Respir. 1992;9 Suppl 4:R261-8.
In order to achieve mediastinal lymph node staging in bronchial cancer, axial mediastinoscopy (combined with left anterior mediastinoscopy for cancers of the left upper lobe) is by far the most efficient and the most reliable technique. Since mediastinoscopy has been part of the investigations that can be made before thoracotomy, the number of exploratory thoracotomies has considerably decreased in all teams, thus reducing at the same time intraoperative mortality. Thoracic CT, which arrived in the diagnostic weaponry for lung cancer a long time after mediastinoscopy, has a major asset in that it allows selecting the patients for whom mediastinoscopy seems to be useful, on the basis of criteria related to the size of mediastinal lymph nodes (10 mm generally being the threshold chosen to perform mediastinoscopy or not). For almost all authors, systematic mediastinoscopy is no longer useful. Similarly, a positive mediastinoscopy must not lead to systematically refuse patients, as the invasion or absence of invasion of a mediastinal lymph node is neither necessary nor sufficient to discuss a surgical indication. While some still automatically refuse all patients with positive mediastinoscopy, most authors still remain very interventionistic for N2 patients selected on very accurate criteria that are analyzed above. Surgery can then be performed at once or, for some authors, after a "neo-adjunctive" therapy, the long-term efficacy of which has unfortunately not been rigorously demonstrated as yet.
为了实现支气管癌的纵隔淋巴结分期,轴向纵隔镜检查(对于左上叶癌联合左前纵隔镜检查)是目前最有效且最可靠的技术。由于纵隔镜检查已成为开胸手术前可进行的检查之一,所有团队的 exploratory thoracotomies 数量都大幅减少,同时降低了术中死亡率。胸部CT在纵隔镜检查很久之后才成为肺癌诊断手段,其主要优势在于能够根据与纵隔淋巴结大小相关的标准(一般以10毫米作为是否进行纵隔镜检查的阈值),选择那些纵隔镜检查似乎有用的患者。对于几乎所有作者来说,系统性纵隔镜检查已不再有用。同样,纵隔镜检查结果为阳性也不应导致一概拒绝患者,因为纵隔淋巴结有无受侵对于讨论手术指征既非必要条件也非充分条件。虽然仍有一些人会自动拒绝所有纵隔镜检查结果为阳性的患者,但大多数作者对于根据上述非常精确的标准选择出的N2患者仍然非常积极干预。然后可以立即进行手术或者,对于一些作者来说,在进行“新辅助”治疗之后进行手术,遗憾的是,其长期疗效尚未得到严格证实。