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[神经组织移植的法律与伦理问题]

[The legal and ethical aspects of nerve tissue transplantation].

作者信息

Sramka M, Rattaj M

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 1992 Nov-Dec(6):12-3.

PMID:1337406
Abstract

The authors have specified the following criteria for the withdrawal of embryonal tissue at their department: 1) only tissue from dead fetus is allowed to be used in neurotransplantation; 2) embryonal tissue is to be obtained after spontaneous abortions from volunteers or from women asking for artificial abortion; 3) the women should be informed about the curative purposes of embryonal tissue voluntary donorship and they must give a written consent; 4) decision on abortion should be separated from the use of embryonal tissue; 5) women should not know recipients; no payments should be made for tissue; 6) the donor is not permitted to impregnate in order to use embryos for research or clinical purposes; 7) sampling of BWR, HBsAG, anti-HIV, cytomegalovirus, herpes I and II is to be made for serologic examinations and that from the cervix for cultivation and sensitivity, as well as ultrasound verification of a germinal age is done in potential donors; 8) consent should be signed to embryonal brain transplantation by recipient or his legitimate deputy if the recipient is certifiable. The above criteria should protect both the donor and the recipient. The use of embryonal tissue cultures seems to be promising. In addition to legal and ethic problems, immunological problems and problems concerning the aseptic withdrawal of embryonal tissue are falling off.

摘要

作者已为其所在科室制定了以下胚胎组织提取标准

1)仅允许将死胎组织用于神经移植;2)胚胎组织应取自志愿者自然流产后或要求人工流产的妇女;3)应告知妇女胚胎组织自愿捐赠的治疗目的,且她们必须给出书面同意;4)堕胎决定应与胚胎组织的使用分开;5)妇女不应知晓接受者;不应为组织支付费用;6)不允许捐赠者为将胚胎用于研究或临床目的而受孕;7)对潜在捐赠者进行血清学检查时要采集BWR、HBsAG、抗HIV、巨细胞病毒、单纯疱疹I型和II型样本,从宫颈采集样本用于培养和药敏试验,以及进行胚胎年龄的超声核实;8)如果接受者可认证,应由接受者或其合法代理人签署胚胎脑移植同意书。上述标准应能保护捐赠者和接受者双方。胚胎组织培养的应用似乎很有前景。除了法律和伦理问题外,免疫问题以及与胚胎组织无菌提取有关的问题也在减少。

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