Tsafaris F, Alexaki E
Department of Biochemistry and Toxicology, Faculty of Veterinary Medicine, Aristotelian University, Thessaloniki, Greece.
Vet Hum Toxicol. 1992 Dec;34(6):510-2.
The transplacental effect of tetraethyl lead or lead acetate on the activity of inorganic pyrophosphatase in brain, liver and kidneys of newborn rats varied with the organ, the lead compound, the dose, and the route and time of administration. Enzyme activity was usually decreased in brain and liver, suggesting adverse effects of lead on metabolism in these organs. The inorganic pyrophosphatase activity was generally increased in kidneys.
四乙基铅或醋酸铅对新生大鼠脑、肝和肾中无机焦磷酸酶活性的经胎盘效应因器官、铅化合物、剂量、给药途径和时间而异。脑和肝中的酶活性通常降低，表明铅对这些器官的代谢有不良影响。肾中的无机焦磷酸酶活性通常升高。
