Goldstein R K, Augustin A, Milz J, Burg G, Lutz J
Department of Dermatology, University of Wuerzburg, Germany.
Adv Exp Med Biol. 1992;316:253-8. doi: 10.1007/978-1-4615-3404-4_29.
Activated neutrophil granulocytes are an important source of oxygen free radicals in acute skin grafts. Lipid peroxidation and immigration of PMNs, indicating inflammatory mechanisms, affect each other to a variable extent. The effect of the scavengers allopurinol and alpha-D-tocopherol on both lipid peroxidation and neutrophilic infiltration was investigated. A possible mechanism for the superior effect of allopurinol compared to vitamin E was discussed.
活化的中性粒细胞是急性皮肤移植中氧自由基的重要来源。脂质过氧化和多形核白细胞的迁移表明炎症机制，它们在不同程度上相互影响。研究了清除剂别嘌呤醇和α-D-生育酚对脂质过氧化和中性粒细胞浸润的影响。讨论了别嘌呤醇比维生素E具有更好效果的可能机制。
