维拉帕米对急性柯萨奇病毒B3型小鼠心肌炎的影响。
Effect of verapamil on acute coxsackievirus B3 murine myocarditis.
作者信息
Xu Y, Yang Y Z, Chen H Z, Jin P Y, Guo Q, Zhao W Z, Yang J H, Cai Q X, Zhou Y C
机构信息
Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Shanghai Medical University.
出版信息
Chin Med J (Engl). 1992 Oct;105(10):818-21.
PMID:1337875
Abstract
The effect of verapamil (Ver) on CVB3 murine myocarditis was investigated. It was found that Ver could aggravate the myocardial inflammation, increase the viral replication in myocardium, and raise mortality in mice with viral myocarditis when the drug was injected within the first 6 days after the CVB3 inoculation.
摘要
研究了维拉帕米（Ver）对柯萨奇病毒B3（CVB3）诱导的小鼠心肌炎的影响。结果发现，在CVB3接种后的前6天内注射Ver，可加重心肌炎症，增加心肌中的病毒复制，并提高病毒性心肌炎小鼠的死亡率。
Zotero 插件