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Role of 5-hydroxytryptamine in prostaglandin E1-induced potentiation of hexobarbitone hypnosis in albino rats.

作者信息

Bhatacharya S K, Mukhopadhyay S N, Debnath P K, Sanyal A K

出版信息

Experientia. 1976;32(7):907-8. doi: 10.1007/BF02003761.

Abstract

PGE1 potentiated, while diclofenac, a prostaglandin synthesis inhibitor, antagonized hexobarbitone hypnosis in rats. PGE1-induced potentiation of hexobarbitone sleep was inhibited by a 5HT synthesis inhibitor and by a 5HT receptor blocker, suggesting that this potentiation is 5HT mediated.

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