Jones E W
Dermatologica. 1976;152 Suppl 1:107-15. doi: 10.1159/000257871.
This histological changes induced by 1 month's applications of various corticorteroids to normal forearm skin were studied. Marked epidermal atrophy was present at 1 month with the more potent steroids, but the dermal changes were minimal or absent. The methods outlined in this study could serve as a useful model for assessing the unwanted atrophogenic action of potent corticosteroid preparations.
研究了将各种皮质类固醇应用于正常前臂皮肤1个月所引起的组织学变化。使用效力更强的类固醇时，1个月时出现明显的表皮萎缩，但真皮变化轻微或未出现。本研究中概述的方法可作为评估强效皮质类固醇制剂不良萎缩作用的有用模型。
