Zhang M
Affiliated Hospital, Shandong Medical University, Jinan.
Zhonghua Yi Xue Za Zhi. 1992 Sep;72(9):550-2, 574.
To noninvasively measure the right ventricular diastolic function, continuous wave Doppler echocardiography was used in 31 patients with tricuspid regurgitation (TR). The right ventricular pressure (RVP) curves were analyzed mathematically, showing that RVP declined exponentially after maximum-dP/dt. The instantaneous RVPs during isovolumetric relaxation were measured from RVP curves and also calculated by using exponential equations. There were high correlations between measured and calculated RVPs (r = 0.83-0.98). The tricuspid regurgitant velocities were recorded by CWD and converted into pressure gradients (PG) using a simplified Bornoulli equation. The instantaneous RVPs were then obtained by adding an assumed right atrial pressure to PGs. The maximum-dP/dt, the instantaneous RVP at the time of -dP/dt max (PO) and the time constant of right ventricular relaxation (T) were calculated from both RVP curves and Doppler spectra. The results showed that there were high correlations of -dP/dt max, PO and T measured by two techniques (r = 0.95, 0.98 and 0.92). We conclude that T can be used to quantitate right ventricular myocardial relaxation, and CWD offers a new technique for noninvasively measuring T in patients with TR.
为了无创测量右心室舒张功能,对31例三尖瓣反流(TR)患者使用连续波多普勒超声心动图。对右心室压力(RVP)曲线进行数学分析,结果显示最大dP/dt后RVP呈指数下降。从RVP曲线测量等容舒张期的瞬时RVP,并使用指数方程进行计算。测量值与计算值之间存在高度相关性(r = 0.83 - 0.98)。用连续波多普勒(CWD)记录三尖瓣反流速度,并使用简化的伯努利方程将其转换为压力阶差(PG)。然后通过将假定的右心房压力与PG相加来获得瞬时RVP。从RVP曲线和多普勒频谱计算最大dP/dt、-dP/dt max时的瞬时RVP(PO)以及右心室舒张时间常数(T)。结果显示,两种技术测量的 -dP/dt max、PO和T之间存在高度相关性(r = 0.95、0.98和0.92)。我们得出结论,T可用于定量右心室心肌舒张,且CWD为无创测量TR患者的T提供了一种新技术。