Ugolev A M, Iezuitova N N, Timofeeva N M, Egorova V V, Nikitina A A, Gordova L A
Fiziol Zh SSSR Im I M Sechenova. 1992 Sep;78(9):76-83.
A wide range of digestive enzymes with different cellular location (membrane, intracellular, Lysosomal) was determined in gastrointestinal organs (stomach, duodenum, jejunum, ileum, colon) as well as in undigestive organs (liver, kidney, spleen) in normal conditions and in altered functional states (fasting, refeeding). High levels of peptidase activity was noted in undigestive organs and the colon as compared to that in the small intestine. Adaptive responses were (revealed not only for a number of membrane enzymes but also for intracellular ones including those in undigestive organs.
在正常状态以及功能改变状态(禁食、重新喂食)下,对胃肠道器官(胃、十二指肠、空肠、回肠、结肠)以及非消化器官(肝脏、肾脏、脾脏)中具有不同细胞定位(膜、细胞内、溶酶体)的多种消化酶进行了测定。与小肠相比,在非消化器官和结肠中观察到高水平的肽酶活性。不仅在许多膜酶中,而且在包括非消化器官中的细胞内酶中都发现了适应性反应。