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[舒洛地尔和乙酰水杨酸对人血小板中类花生酸合成的影响]

[The effect of suloctidil and acetylsalicylic acid on eicosanoid synthesis in human platelets].

作者信息

Tkaczewski W, Buczyński A, Dziedziczak-Buczyńska M, Wachowicz B, Kedziora J

机构信息

III Kliniki Chorób Wewnetrznych IMW.

出版信息

Pol Tyg Lek. 1992;47(42-43):970-1.

PMID:1338656
Abstract

The study aimed at comparing an effect of suloctidil and acetylsalicylic acid on malonyldialdehyde levels resulting from the arachidonic acid metabolism in blood platelets. It was shown that inhibitory effect of suloctidil is more potent than that of acetylsalicylic acid. Therefore the first is more inhibitor of an enzymatic metabolism of arachidonate in blood platelets than the latter.

摘要

该研究旨在比较舒洛地尔和乙酰水杨酸对血小板中花生四烯酸代谢产生的丙二醛水平的影响。结果表明,舒洛地尔的抑制作用比乙酰水杨酸更强。因此,前者比后者更能抑制血小板中花生四烯酸的酶促代谢。

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Pol Tyg Lek. 1992;47(42-43):970-1.
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